稳定化生长激素释放激素类似物
Identity, purity and main-peak area are checked by reversed-phase HPLC against an in-house reference standard for this sequence. The chromatogram you see on the certificate of analysis is generated at this exact bench, by the analysts who release the batch.
When a sequence moves from milligram research lots to multi-gram research supply, the same chemistry is transferred onto jacketed stainless reactors. Temperature, agitation and reagent equivalents are logged in real time so that the larger batch matches the analytical fingerprint of the small one.
替莫瑞林是44氨基酸GHRH的稳定化类似物，N端连接反式3-己烯酰基以提高血浆稳定性。
选择性作用于垂体前叶GHRH受体，促进生长激素脉冲式分泌，恢复生理性GH/IGF-1轴节律。
用于内脏脂肪沉积、HIV相关脂肪萎缩、认知与衰老相关GH轴变化的研究模型。
44氨基酸序列，N端3-己烯酰修饰，结构与天然hGHRH高度同源。
