01
概述
Epitalon（艾普他隆）为四肽Ala-Glu-Asp-Gly，源自松果体提取物Epithalamin的活性结构。
02
药理与机制
在体外与动物模型中显示对端粒酶活性、褪黑素分泌节律与神经内分泌调节的影响。
03
研究方向
R.01
松果体衍生四肽
细胞复制性衰老、生物钟与神经内分泌轴老化的经典工具分子。
04
结构信息
四肽序列Ala-Glu-Asp-Gly，结构简洁，水溶性良好。
氨基酸序列
Ala-Glu-Asp-Gly
仅供科研用途。不构成医疗建议，不用于诊断或治疗。
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lyophilized
AEDG · 端粒研究短肽
Epitalon
松果体衍生四肽
技术数据LZH-011
- 代号
- AEDG
- 分子式
- C14H22N4O9
- 分子量
- 390.4 Da
- 半衰期
- Short plasma (~minutes); biological effects persist through gene regulation
- 研究给药途径
- Subcutaneous / intranasal (research)
- 分子靶点
- hTERT promoter modulation (in vitro) · pineal neuroendocrine axis
- 发现 / 披露
- Khavinson lab, St. Petersburg, 1980s-1990s
- 目标纯度
- ≥ 98%
- 建议储存
- −20°C 避光，复溶后 2~8°C
别名
Epithalon, AEDG tetrapeptide
外观
White lyophilized powder
溶解性
Freely water soluble
氨基酸序列
Ala-Glu-Asp-Gly
FIG. 201Analytical Lab
Identity, purity and main-peak area are checked by reversed-phase HPLC against an in-house reference standard for this sequence. The chromatogram you see on the certificate of analysis is generated at this exact bench, by the analysts who release the batch.
FIG. 202Scale-up Operations
When a sequence moves from milligram research lots to multi-gram research supply, the same chemistry is transferred onto jacketed stainless reactors. Temperature, agitation and reagent equivalents are logged in real time so that the larger batch matches the analytical fingerprint of the small one.