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KED · Vascular research

Vesugen

Vascular matrix bioregulatory tripeptide

Ficha técnicaLZH-016
Código
KED
Semivida
Short plasma; transcriptional effects persist
Vía de investigación
SC / sublingual (research)
Dianas moleculares
Endothelial gene expression modulation
Descubrimiento / divulgación
Khavinson group, 2000s
Pureza objetivo
≥ 98%
Almacenamiento recomendado
−20 °C, protegido de la luz. De 2 a 8 °C tras la reconstitución.
Sinónimos
KED tripeptide
Aspecto
White lyophilized powder
Solubilidad
Water soluble
Secuencia
Lys-Glu-Asp
Analistas revisando el cromatograma de HPLC del lote actual
FIG. 201Analytical Lab

Identity, purity and main-peak area are checked by reversed-phase HPLC against an in-house reference standard for this sequence. The chromatogram you see on the certificate of analysis is generated at this exact bench, by the analysts who release the batch.

Técnico supervisando un reactor de acero inoxidable durante el escalado
FIG. 202Scale-up Operations

When a sequence moves from milligram research lots to multi-gram research supply, the same chemistry is transferred onto jacketed stainless reactors. Temperature, agitation and reagent equivalents are logged in real time so that the larger batch matches the analytical fingerprint of the small one.

01

Descripción general

Vesugen is the Lys-Glu-Asp (KED) tripeptide within the Khavinson bioregulator family, focused on vascular wall and endothelial cell research.

02

Farmacología y mecanismo

Modulates endothelial gene expression, linked to transcription of vascular homeostasis and endothelial function factors.

03

Áreas de investigación

R.01
Vascular matrix bioregulatory tripeptide

Tool molecule in vascular aging, endothelial function and vascular matrix biology studies.

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Notas estructurales

Tripeptide Lys-Glu-Asp.

Secuencia
Lys-Glu-Asp
Uso exclusivo en investigación. No constituye asesoramiento médico ni se destina al diagnóstico o tratamiento.