TB-500 + BPC-157

A two-peptide toolkit for connective tissue and vascular repair research

Ficha técnicaLZH-007

Código: Regenerative duo
Semivida: TB-500: hours; BPC-157: short plasma, longer tissue residence
Vía de investigación: Subcutaneous / IM (research)
Dianas moleculares: G-actin (TB-500) · VEGFR2 / NO-pathway / GH-R upregulation (BPC-157)
Descubrimiento / divulgación: TB-500: synthetic Tβ4 active fragment, 1990s; BPC-157: Sikiric lab, Zagreb, 1991
Pureza objetivo: ≥ 98%
Almacenamiento recomendado: −20 °C, protegido de la luz. De 2 a 8 °C tras la reconstitución.

Sinónimos

Thymosin β4 fragment (1-4 + 17-23) + Body Protection Compound 157

Aspecto

White lyophilized powder

Solubilidad

Both highly water soluble

Secuencia

TB-500: Ac-LKKTETQ | BPC-157: GEPPPGKPADDAGLV

Analistas revisando el cromatograma de HPLC del lote actual — FIG. 201Analytical Lab
Identity, purity and main-peak area are checked by reversed-phase HPLC against an in-house reference standard for this sequence. The chromatogram you see on the certificate of analysis is generated at this exact bench, by the analysts who release the batch.

Técnico supervisando un reactor de acero inoxidable durante el escalado — FIG. 202Scale-up Operations
When a sequence moves from milligram research lots to multi-gram research supply, the same chemistry is transferred onto jacketed stainless reactors. Temperature, agitation and reagent equivalents are logged in real time so that the larger batch matches the analytical fingerprint of the small one.

Descripción general

TB-500 is an active fragment of thymosin beta 4. BPC-157 is a stable pentadecapeptide derived from a gastric protective protein.

Both are commonly used as a tool combination in tissue repair research.

Farmacología y mecanismo

TB-500 binds G-actin and supports cell migration and neovascularization. BPC-157 modulates VEGFR2, nitric oxide pathways and tendon fibroblast activity.