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lyophilized

ACTH(4-7) analog · Neurocognitive research

Semax

Stabilized ACTH(4-7) analog

Ficha técnicaLZH-015

Código: ACTH(4-7) analog
Semivida: Short plasma; central activity hours
Vía de investigación: Intranasal (research)
Dianas moleculares: BDNF / NGF upregulation · monoamine modulation
Descubrimiento / divulgación: Institute of Molecular Genetics, Moscow, 1980s
Pureza objetivo: ≥ 98%
Almacenamiento recomendado: −20 °C, protegido de la luz. De 2 a 8 °C tras la reconstitución.

Sinónimos

ACTH(4-7) PGP analog

Aspecto

White lyophilized powder

Solubilidad

Water soluble

Secuencia

Met-Glu-His-Phe-Pro-Gly-Pro

Analistas revisando el cromatograma de HPLC del lote actual — FIG. 201Analytical Lab
Identity, purity and main-peak area are checked by reversed-phase HPLC against an in-house reference standard for this sequence. The chromatogram you see on the certificate of analysis is generated at this exact bench, by the analysts who release the batch.

Técnico supervisando un reactor de acero inoxidable durante el escalado — FIG. 202Scale-up Operations
When a sequence moves from milligram research lots to multi-gram research supply, the same chemistry is transferred onto jacketed stainless reactors. Temperature, agitation and reagent equivalents are logged in real time so that the larger batch matches the analytical fingerprint of the small one.

01

Descripción general

Semax is a synthetic heptapeptide derived from the ACTH(4-7) sequence with a C-terminal Pro-Gly-Pro extension improving stability.

02

Farmacología y mecanismo

Upregulates BDNF and neurotrophin expression, modulates central monoamines and influences neural plasticity.

03

Áreas de investigación

R.01

Stabilized ACTH(4-7) analog

Classical tool peptide in ischemic brain injury, attention and learning memory studies.

04

Notas estructurales

Heptapeptide Met-Glu-His-Phe-Pro-Gly-Pro.

Secuencia

Met-Glu-His-Phe-Pro-Gly-Pro

Uso exclusivo en investigación. No constituye asesoramiento médico ni se destina al diagnóstico o tratamiento.

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