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TP-7 analog · Anxiolytic and cognitive research

Selank

Stabilized analog of tuftsin

Ficha técnicaLZH-014
Código
TP-7 analog
Semivida
Short plasma (~minutes); central effects persist hours
Vía de investigación
Intranasal (research)
Dianas moleculares
GABAergic, monoaminergic and BDNF expression modulation
Descubrimiento / divulgación
Russian Academy of Sciences / Institute of Molecular Genetics, 1990s
Pureza objetivo
≥ 98%
Almacenamiento recomendado
−20 °C, protegido de la luz. De 2 a 8 °C tras la reconstitución.
Sinónimos
TP-7 stabilized analog
Aspecto
White lyophilized powder
Solubilidad
Water soluble
Secuencia
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Analistas revisando el cromatograma de HPLC del lote actual
FIG. 201Analytical Lab

Identity, purity and main-peak area are checked by reversed-phase HPLC against an in-house reference standard for this sequence. The chromatogram you see on the certificate of analysis is generated at this exact bench, by the analysts who release the batch.

Técnico supervisando un reactor de acero inoxidable durante el escalado
FIG. 202Scale-up Operations

When a sequence moves from milligram research lots to multi-gram research supply, the same chemistry is transferred onto jacketed stainless reactors. Temperature, agitation and reagent equivalents are logged in real time so that the larger batch matches the analytical fingerprint of the small one.

01

Descripción general

Selank is a synthetic analog of the natural tuftsin peptide, a heptapeptide with a C-terminal stabilizing modification.

02

Farmacología y mecanismo

Modulates GABAergic, monoaminergic and neurotrophic factor expression, affecting brain regions linked to stress and cognition.

03

Áreas de investigación

R.01
Stabilized analog of tuftsin

Tool peptide in anxiety models, cognitive performance and immune-neuro modulation research.

04

Notas estructurales

Heptapeptide Thr-Lys-Pro-Arg-Pro-Gly-Pro with C-terminal Pro extension.

Secuencia
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Uso exclusivo en investigación. No constituye asesoramiento médico ni se destina al diagnóstico o tratamiento.
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