Descripción general
KPV is the C-terminal tripeptide fragment (Lys-Pro-Val) of alpha melanocyte stimulating hormone, retaining its key anti-inflammatory activity.
Farmacología y mecanismo
Downregulates NF-kB signaling and suppresses pro-inflammatory cytokine expression, with barrier-protective effects in gut and mucosal models.
Áreas de investigación
Tool molecule for inflammatory bowel disease, skin inflammation and mucosal barrier studies.
Notas estructurales
Tripeptide Lys-Pro-Val. Small molecular weight allows multiple delivery routes.


