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lyophilized

Delta sleep peptide · Sleep and neuroendocrine

DSIP

Delta sleep inducing peptide

Ficha técnicaLZH-013

Código: Delta sleep peptide
Fórmula: C35H48N10O15
Masa molecular: 848.8 Da
Semivida: ~7-15 min (plasma)
Vía de investigación: Subcutaneous / IV (research)
Dianas moleculares: Neuroendocrine modulation; precise receptor not fully resolved
Descubrimiento / divulgación: Schoenenberger & Monnier, Bern, 1977
Pureza objetivo: ≥ 98%
Almacenamiento recomendado: −20 °C, protegido de la luz. De 2 a 8 °C tras la reconstitución.

Sinónimos

Delta sleep-inducing peptide

Aspecto

White lyophilized powder

Solubilidad

Water soluble

Secuencia

Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

Analistas revisando el cromatograma de HPLC del lote actual — FIG. 201Analytical Lab
Identity, purity and main-peak area are checked by reversed-phase HPLC against an in-house reference standard for this sequence. The chromatogram you see on the certificate of analysis is generated at this exact bench, by the analysts who release the batch.

Técnico supervisando un reactor de acero inoxidable durante el escalado — FIG. 202Scale-up Operations
When a sequence moves from milligram research lots to multi-gram research supply, the same chemistry is transferred onto jacketed stainless reactors. Temperature, agitation and reagent equivalents are logged in real time so that the larger batch matches the analytical fingerprint of the small one.

01

Descripción general

DSIP is a nonapeptide originally isolated from rabbit brain perfusate, with activity in regulating slow-wave sleep.

02

Farmacología y mecanismo

Modulates neurotransmitter release and the circadian cortisol rhythm, with a buffering effect on the stress axis.

03

Áreas de investigación

R.01

Delta sleep inducing peptide

A classical tool peptide for sleep physiology, stress response and neuroendocrine rhythm studies.

04

Notas estructurales

Nonapeptide Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu.

Secuencia

Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

Uso exclusivo en investigación. No constituye asesoramiento médico ni se destina al diagnóstico o tratamiento.

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