Lizhi
Volver a la bibliotecaEntrada · LZH-010
MOTS-c + 5-Amino-1MQ + NAD+ · Metabolic longevity complex

Biomtide

A mitochondrial peptide and NAD+ precursor research stack

Ficha técnicaLZH-010
Código
MOTS-c + 5-Amino-1MQ + NAD+
Semivida
MOTS-c: ~hours; NAD+: rapid turnover; 5-Amino-1MQ: oral t½ ~hours
Vía de investigación
Subcutaneous (peptide); oral (small molecules) (research)
Dianas moleculares
AMPK axis (MOTS-c) · NNMT inhibition (5-Amino-1MQ) · sirtuins / PARPs (NAD+)
Descubrimiento / divulgación
MOTS-c identified by Lee & Cohen, USC, 2015
Pureza objetivo
≥ 98%
Almacenamiento recomendado
−20 °C, protegido de la luz. De 2 a 8 °C tras la reconstitución.
Sinónimos
MOTS-c + 5-Amino-1MQ + NAD+
Aspecto
White to slightly cream lyophilized powder
Solubilidad
MOTS-c and NAD+ water soluble; 5-Amino-1MQ DMSO/water
Secuencia
MOTS-c: MRWQEMGYIFYPRKLR (16 aa, mtDNA 12S-rRNA derived)
Analistas revisando el cromatograma de HPLC del lote actual
FIG. 201Analytical Lab

Identity, purity and main-peak area are checked by reversed-phase HPLC against an in-house reference standard for this sequence. The chromatogram you see on the certificate of analysis is generated at this exact bench, by the analysts who release the batch.

Técnico supervisando un reactor de acero inoxidable durante el escalado
FIG. 202Scale-up Operations

When a sequence moves from milligram research lots to multi-gram research supply, the same chemistry is transferred onto jacketed stainless reactors. Temperature, agitation and reagent equivalents are logged in real time so that the larger batch matches the analytical fingerprint of the small one.

01

Descripción general

Biomtide is a research preparation combining the mitochondrial-derived peptide MOTS-c, the NNMT inhibitor 5-Amino-1MQ and NAD+, used to explore synergistic metabolic and aging interventions.

02

Farmacología y mecanismo

MOTS-c modulates AMPK and insulin sensitivity. 5-Amino-1MQ inhibits NNMT, preserving the SAM methyl pool.

NAD+ acts as a cofactor supporting sirtuin and mitochondrial function.

03

Áreas de investigación

R.01
A mitochondrial peptide and NAD+ precursor research stack

Used in combined models of metabolic syndrome, muscle function, mitochondrial biogenesis and aging intervention.

04

Notas estructurales

MOTS-c: 16 amino acid mitochondrial derived peptide. 5-Amino-1MQ: small molecule methyl quinoline. NAD+: native cofactor.

Secuencia
MOTS-c: MRWQEMGYIFYPRKLR (16 aa, mtDNA 12S-rRNA derived)
Uso exclusivo en investigación. No constituye asesoramiento médico ni se destina al diagnóstico o tratamiento.