Lizhi
KED · Vascular research

Vesugen

Vascular matrix bioregulatory tripeptide

Fiche techniqueLZH-016
Code
KED
Demi-vie
Short plasma; transcriptional effects persist
Voie de recherche
SC / sublingual (research)
Cibles moléculaires
Endothelial gene expression modulation
Découverte / divulgation
Khavinson group, 2000s
Pureté cible
≥ 98 %
Conservation recommandée
−20 °C, à l'abri de la lumière. De 2 à 8 °C après reconstitution.
Synonymes
KED tripeptide
Aspect
White lyophilized powder
Solubilité
Water soluble
Séquence
Lys-Glu-Asp
Analystes examinant le chromatogramme HPLC du lot en cours
FIG. 201Analytical Lab

Identity, purity and main-peak area are checked by reversed-phase HPLC against an in-house reference standard for this sequence. The chromatogram you see on the certificate of analysis is generated at this exact bench, by the analysts who release the batch.

Technicien surveillant un réacteur en acier inoxydable pendant la montée en échelle
FIG. 202Scale-up Operations

When a sequence moves from milligram research lots to multi-gram research supply, the same chemistry is transferred onto jacketed stainless reactors. Temperature, agitation and reagent equivalents are logged in real time so that the larger batch matches the analytical fingerprint of the small one.

01

Vue d'ensemble

Vesugen is the Lys-Glu-Asp (KED) tripeptide within the Khavinson bioregulator family, focused on vascular wall and endothelial cell research.

02

Pharmacologie et mécanisme

Modulates endothelial gene expression, linked to transcription of vascular homeostasis and endothelial function factors.

03

Domaines de recherche

R.01
Vascular matrix bioregulatory tripeptide

Tool molecule in vascular aging, endothelial function and vascular matrix biology studies.

04

Notes structurales

Tripeptide Lys-Glu-Asp.

Séquence
Lys-Glu-Asp
Réservé à un usage de recherche. Ne constitue pas un avis médical et n'est destiné ni au diagnostic ni au traitement.