Lizhi
← Retour à la bibliothèqueEntrée · LZH-013
Delta sleep peptide · Sleep and neuroendocrine

DSIP

Delta sleep inducing peptide

Fiche techniqueLZH-013
Code
Delta sleep peptide
Formule
C35H48N10O15
Masse moléculaire
848.8 Da
Demi-vie
~7-15 min (plasma)
Voie de recherche
Subcutaneous / IV (research)
Cibles moléculaires
Neuroendocrine modulation; precise receptor not fully resolved
Découverte / divulgation
Schoenenberger & Monnier, Bern, 1977
Pureté cible
≥ 98 %
Conservation recommandée
−20 °C, à l'abri de la lumière. De 2 à 8 °C après reconstitution.
Synonymes
Delta sleep-inducing peptide
Aspect
White lyophilized powder
Solubilité
Water soluble
Séquence
Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Analystes examinant le chromatogramme HPLC du lot en cours
FIG. 201Analytical Lab

Identity, purity and main-peak area are checked by reversed-phase HPLC against an in-house reference standard for this sequence. The chromatogram you see on the certificate of analysis is generated at this exact bench, by the analysts who release the batch.

Technicien surveillant un réacteur en acier inoxydable pendant la montée en échelle
FIG. 202Scale-up Operations

When a sequence moves from milligram research lots to multi-gram research supply, the same chemistry is transferred onto jacketed stainless reactors. Temperature, agitation and reagent equivalents are logged in real time so that the larger batch matches the analytical fingerprint of the small one.

01

Vue d'ensemble

DSIP is a nonapeptide originally isolated from rabbit brain perfusate, with activity in regulating slow-wave sleep.

02

Pharmacologie et mécanisme

Modulates neurotransmitter release and the circadian cortisol rhythm, with a buffering effect on the stress axis.

03

Domaines de recherche

R.01
Delta sleep inducing peptide

A classical tool peptide for sleep physiology, stress response and neuroendocrine rhythm studies.

04

Notes structurales

Nonapeptide Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu.

Séquence
Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Réservé à un usage de recherche. Ne constitue pas un avis médical et n'est destiné ni au diagnostic ni au traitement.
Molécules apparentées

Molécules apparentées

Catalogue complet →
GLP-1 RA4113.6 Da
Semaglutide
Metabolic regulation
Open →
GIP / GLP-14813.5 Da
Tirzepatide
Dual receptor agonist
Open →
GIP / GLP-1 / GCG
Retatrutide
Triple receptor agonist
Open →
Elamipretide639.8 Da
SS-31
Mitochondrial targeting
Open →
GHRH analog
Tesamorelin
GHRH analog
Open →
GHRH + GHRP
CJC-1295 + Ipamorelin
GH pulse combination
Open →