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MOTS-c + 5-Amino-1MQ + NAD+ · Metabolic longevity complex

Biomtide

A mitochondrial peptide and NAD+ precursor research stack

Fiche techniqueLZH-010
Code
MOTS-c + 5-Amino-1MQ + NAD+
Demi-vie
MOTS-c: ~hours; NAD+: rapid turnover; 5-Amino-1MQ: oral t½ ~hours
Voie de recherche
Subcutaneous (peptide); oral (small molecules) (research)
Cibles moléculaires
AMPK axis (MOTS-c) · NNMT inhibition (5-Amino-1MQ) · sirtuins / PARPs (NAD+)
Découverte / divulgation
MOTS-c identified by Lee & Cohen, USC, 2015
Pureté cible
≥ 98 %
Conservation recommandée
−20 °C, à l'abri de la lumière. De 2 à 8 °C après reconstitution.
Synonymes
MOTS-c + 5-Amino-1MQ + NAD+
Aspect
White to slightly cream lyophilized powder
Solubilité
MOTS-c and NAD+ water soluble; 5-Amino-1MQ DMSO/water
Séquence
MOTS-c: MRWQEMGYIFYPRKLR (16 aa, mtDNA 12S-rRNA derived)
Analystes examinant le chromatogramme HPLC du lot en cours
FIG. 201Analytical Lab

Identity, purity and main-peak area are checked by reversed-phase HPLC against an in-house reference standard for this sequence. The chromatogram you see on the certificate of analysis is generated at this exact bench, by the analysts who release the batch.

Technicien surveillant un réacteur en acier inoxydable pendant la montée en échelle
FIG. 202Scale-up Operations

When a sequence moves from milligram research lots to multi-gram research supply, the same chemistry is transferred onto jacketed stainless reactors. Temperature, agitation and reagent equivalents are logged in real time so that the larger batch matches the analytical fingerprint of the small one.

01

Vue d'ensemble

Biomtide is a research preparation combining the mitochondrial-derived peptide MOTS-c, the NNMT inhibitor 5-Amino-1MQ and NAD+, used to explore synergistic metabolic and aging interventions.

02

Pharmacologie et mécanisme

MOTS-c modulates AMPK and insulin sensitivity. 5-Amino-1MQ inhibits NNMT, preserving the SAM methyl pool.

NAD+ acts as a cofactor supporting sirtuin and mitochondrial function.

03

Domaines de recherche

R.01
A mitochondrial peptide and NAD+ precursor research stack

Used in combined models of metabolic syndrome, muscle function, mitochondrial biogenesis and aging intervention.

04

Notes structurales

MOTS-c: 16 amino acid mitochondrial derived peptide. 5-Amino-1MQ: small molecule methyl quinoline. NAD+: native cofactor.

Séquence
MOTS-c: MRWQEMGYIFYPRKLR (16 aa, mtDNA 12S-rRNA derived)
Réservé à un usage de recherche. Ne constitue pas un avis médical et n'est destiné ni au diagnostic ni au traitement.